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1

Enhanced engraftment, proliferation, and therapeutic potential in heart using optimized human iPSC-derived cardiomyocytes

Funakoshi, Shunsuke, Miki, Kenji, Takaki, Tadashi, Okubo, Chikako, Hatani, Takeshi, Chonabayashi, Kazuhisa, Nishikawa, Misato, Takei, Ikue, Oishi, Akiko, Narita, Megumi, Hoshijima, Masahiko, Kimura, T

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 3.29 MB

english, 2016

2

Adding a new dimension to cardiac nano-architecture using electron microscopy: Coupling membrane excitation to calcium signaling

Das, Tapaswini, Hoshijima, Masahiko

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2013

Language:

english

File:

PDF, 965 KB

english, 2013

3

Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers

Sindhu M. Gopalan, Chris Flaim, Sangeeta N. Bhatia, Masahiko Hoshijima, Ralph Knoell, Kenneth R. Chien, Jeffrey H. Omens, Andrew D. McCulloch

Journal:

Biotechnology and Bioengineering

Year:

2003

Language:

english

File:

PDF, 299 KB

english, 2003

4

Role of protein kinase C in transmembrane signaling

Yoshimi Takai, Kozo Kaibuchi, Terutaka Tsuda, Masahiko Hoshijima

Journal:

Journal of Cellular Biochemistry

Year:

1985

Language:

english

File:

PDF, 756 KB

english, 1985

5

Cardiac mechanotransduction and implications for heart disease

Ralph Knöll, Masahiko Hoshijima, Kenneth Chien

Journal:

Journal of Molecular Medicine

Year:

2003

Language:

english

File:

PDF, 229 KB

english, 2003

6

In vivo Gene Transfer of Dominant-Negative Rho-Kinase Induces Regression of Coronary Arteriosclerosis in Pigs

KUNIO MORISHIGE, HIROAKI SHIMOKAWA, YASUHIRO ETO, MASAHIKO HOSHIJIMA, KOZO KAIBUCHI, AKIRA TAKESHITA

Journal:

Annals of the New York Academy of Sciences

Year:

2001

Language:

english

File:

PDF, 4.87 MB

english, 2001

7

Unravelling Ras signals in cardiovascular disease

Chien, Kenneth R., Hoshijima, Masahiko

Journal:

Nature Cell Biology

Year:

2004

Language:

english

File:

PDF, 106 KB

english, 2004

8

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

Yasukawa, Hideo, Ohishi, Masanobu, Mori, Hiroyuki, Murakami, Masaaki, Chinen, Takatoshi, Aki, Daisuke, Hanada, Toshikatsu, Takeda, Kiyoshi, Akira, Shizuo, Hoshijima, Masahiko

Journal:

Nature Immunology

Year:

2003

Language:

english

File:

PDF, 1.12 MB

english, 2003

9

Calcium and heart failure: the cycle game

Chien, Kenneth R., Ross, John, Hoshijima, Masahiko

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 332 KB

english, 2003

10

Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery

Hoshijima, Masahiko, Ikeda, Yasuhiro, Iwanaga, Yoshitaka, Minamisawa, Susumu, Date, Moto-o, Gu, Yusu, Iwatate, Mitsuo, Li, Manxiang, Wang, Lili, Wilson, James M., Wang, Yibin, Ross, John, Chien, Kenne

Journal:

Nature Medicine

Year:

2002

Language:

english

File:

PDF, 896 KB

english, 2002

11

Models of Dilated Cardiomyopathy in Small Animals and Novel Positive Inotropic Therapies

MASAHIKO HOSHIJIMA

Journal:

Annals of the New York Academy of Sciences

Year:

2004

File:

PDF, 1.41 MB

2004

12

Phosphatidylinositol turnover in platelet activation; Calcium mobilization and protein phosphorylation

Kozo Kaibuchi, Kimihiko Sano, Masahiko Hoshijima, Yoshimi Takai, Yasutomi Nishizuka

Journal:

Year:

1982

Language:

english

File:

PDF, 804 KB

english, 1982

13

LIM domains regulate protein kinase C activity: A novel molecular function

Andrés D. Maturana, Noritaka Nakagawa, Nobuo Yoshimoto, Kenji Tatematsu, Masahiko Hoshijima, Katsuyuki Tanizawa, Shun'ichi Kuroda

Journal:

Cellular Signalling

Year:

2011

Language:

english

File:

PDF, 696 KB

english, 2011

14

Gene therapy targeted at calcium handling as an approach to the treatment of heart failure

Masahiko Hoshijima

Journal:

Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 612 KB

english, 2005

15

ENH, Containing PDZ and LIM Domains, Heart/Skeletal Muscle-Specific Protein, Associates with Cytoskeletal Proteins through the PDZ Domain

Noritaka Nakagawa, Masahiko Hoshijima, Miho Oyasu, Naoaki Saito, Katsuyuki Tanizawa, Shun'ichi Kuroda

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 223 KB

english, 2000

16

Similar physical and kinetic properties of rat brain synaptic membrane and cytosol phosphoinositide phospholipases C

Osamu Kozawa, Masahiko Hoshijima, Tetsuji Tanimoto, Toshihiko Ohmori, Yoshimi Takai

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 574 KB

english, 1987

17

Enhancement of fibroblast growth factor-induced diacylglycerol formation and protein kinase C activation by colon tumor-promoting bile acid in Swiss 3T3 cells: Different modes of action between bile acid and phorbol ester

Yoshifumi Takeyama, Tetsuji Tanimoto, Masahiko Hoshijima, Kozo Kaibuchi, Harumasa Ohyanagi, Yoichi Saitoh, Yoshimi Takai

Journal:

Year:

1986

Language:

english

File:

PDF, 562 KB

english, 1986

18

Binding of ras p21 to bands 4.2 and 6 of human erythrocyte membranes

Tetsuji Tanimoto, Masahiko Hoshijima, Masahito Kawata, Katsuhiko Yamamoto, Toshihiko Ohmori, Hiroshi Shiku, Hirofumi Nakano, Yoshimi Takai

Journal:

Year:

1988

Language:

english

File:

PDF, 610 KB

english, 1988

19

Angiotensin II transduces its signal to focal adhesions via angiotensin II type 1 receptors in vascular smooth muscle cells

Masanori Okuda, Yasuhiro Kawahara, Ichiro Nakayama, Masahiko Hoshijima, Mitsuhiro Yokoyama

Journal:

Year:

1995

Language:

english

File:

PDF, 539 KB

english, 1995

20

Small GTP-binding proteins in bovine heart

Masahiko Hoshijima, Mitsuhiro Yokoyama, Yoshimi Takai

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1992

Language:

english

File:

PDF, 98 KB

english, 1992

21

Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies

Susumu Minamisawa, Jin Oshikawa, Hiroshi Takeshima, Masahiko Hoshijima, Yibin Wang, Kenneth R. Chien, Yoshihiro Ishikawa, Rumiko Matsuoka

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 517 KB

english, 2004

22

PKCε–PKD1 signaling complex at Z-discs plays a pivotal role in the cardiac hypertrophy induced by G-protein coupling receptor agonists

Miki Iwata, Andrés Maturana, Masahiko Hoshijima, Kenji Tatematsu, Toshihide Okajima, Jackie R. Vandenheede, Johan Van Lint, Katsuyuki Tanizawa, Shun’ichi Kuroda

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 1.34 MB

english, 2005

23

TRPC3-mediated Ca2+ influx contributes to Rac1-mediated production of reactive oxygen species in MLP-deficient mouse hearts

Naoyuki Kitajima, Kunihiro Watanabe, Sachio Morimoto, Yoji Sato, Shigeki Kiyonaka, Masahiko Hoshijima, Yasuhiro Ikeda, Michio Nakaya, Tomomi Ide, Yasuo Mori, Hitoshi Kurose, Motohiro Nishida

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 617 KB

english, 2011

24

Cardiac-Specific Deletion of SOCS3 Prevented Myocardial Apoptosis After Acute Myocardial Infarction Through Inhibiting Mitochondrial Damage

Toyoharu Oba, Hideo Yasukawa, Ken-Ichirou Sasaki, Nobuyoshi Futamata, Kazutoshi Mawatari, Sachiko Kyougoku, Takanobu Nagata, Masahiko Hoshijima, Kirk Knowlton, Tsutomu Imaizumi

Journal:

Journal of Cardiac Failure

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

25

Three-dimensional geometric modeling of membrane-bound organelles in ventricular myocytes: Bridging the gap between microscopic imaging and mathematical simulation

Zeyun Yu, Michael J. Holst, Takeharu Hayashi, Chandrajit L. Bajaj, Mark H. Ellisman, J. Andrew McCammon, Masahiko Hoshijima

Journal:

Journal of Structural Biology

Year:

2008

Language:

english

File:

PDF, 857 KB

english, 2008

26

Distinct roles of HF-1b/Sp4 in ventricular and neural crest cells lineages affect cardiac conduction system development

Tara R. St. Amand, Jonathan T. Lu, Monica Zamora, Yusu Gu, Janelle Stricker, Masahiko Hoshijima, Jonathan A. Epstein, John J. Ross Jr., Pilar Ruiz-Lozano, Kenneth R. Chien

Journal:

Developmental Biology

Year:

2006

Language:

english

File:

PDF, 659 KB

english, 2006

27

Young MLP deficient mice show diastolic dysfunction before the onset of dilated cardiomyopathy

Ilka Lorenzen-Schmidt, Bruno D. Stuyvers, Henk E.D.J. ter Keurs, Moto-o Date, Masahiko Hoshijima, Kenneth R. Chien, Andrew D. McCulloch, Jeffrey H. Omens

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2005

Language:

english

File:

PDF, 424 KB

english, 2005

28

Cardiac origin of smooth muscle cells in the inflow tract

Haruko Nakano, Estrelania Williams, Masahiko Hoshijima, Mika Sasaki, Susumu Minamisawa, Kenneth R. Chien, Atsushi Nakano

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2011

Language:

english

File:

PDF, 2.50 MB

english, 2011

29

Different sensitivity to phorbol esters and pertussis toxin of bombesin- and platelet-derived growth factor-induced, phospholipase C-mediated hydrolysis of phosphoinositides in NIH/3T3 cells

Masahiko Hoshijima, Takashi Ueda, Yasuo Hamamori, Toshihiko Ohmori, Yoshimi Takai

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 575 KB

english, 1988

30

Phosphorylation by cyclic AMP-dependent protein kinase of a human platelet Mr 22,000 GTP-binding protein (smg p21) having the same putative effector domain as the ras gene products

Masahiko Hoshijima, Akira Kikuchi, Masahito Kawata, Toshihiko Ohmori, Eikichi Hashimoto, Hirohei Yamamura, Yoshimi Takai

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 759 KB

english, 1988

31

Chronic Phospholamban–Sarcoplasmic Reticulum Calcium ATPase Interaction Is the Critical Calcium Cycling Defect in Dilated Cardiomyopathy

Susumu Minamisawa, Masahiko Hoshijima, Guoxiang Chu, Christopher A Ward, Konrad Frank, Yusu Gu, Maryann E Martone, Yibin Wang, John Ross Jr., Evangelia G Kranias, Wayne R Giles, Kenneth R Chien

Journal:

Year:

1999

Language:

english

File:

PDF, 289 KB

english, 1999

32

A Defect in the Kv Channel-Interacting Protein 2 (KChIP2) Gene Leads to a Complete Loss of Ito and Confers Susceptibility to Ventricular Tachycardia

Hai-Chien Kuo, Ching-Feng Cheng, Robert B. Clark, Jim J.-C. Lin, Jenny L.-C. Lin, Masahiko Hoshijima, Vân T.B. Nguyêñ-Trân, Yusu Gu, Yasuhiro Ikeda, Po-Hsien Chu, John Ross Jr., Wayne R. Giles, Kennet

Journal:

Year:

2001

Language:

english

File:

PDF, 725 KB

english, 2001

33

The Cardiac Mechanical Stretch Sensor Machinery Involves a Z Disc Complex that Is Defective in a Subset of Human Dilated Cardiomyopathy

Ralph Knöll, Masahiko Hoshijima, Hal M. Hoffman, Veronika Person, Ilka Lorenzen-Schmidt, Marie-Louise Bang, Takeharu Hayashi, Nobuyuki Shiga, Hideo Yasukawa, Wolfgang Schaper, William McKenna, Mitsuhi

Journal:

Year:

2002

Language:

english

File:

PDF, 756 KB

english, 2002

34

Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit

Johan Hake, Andrew G. Edwards, Zeyun Yu, Peter M. Kekenes-Huskey, Anushka P. Michailova, J. Andrew McCammon, Michael J. Holst, Masahiko Hoshijima, Andrew D. McCulloch

Journal:

The Journal of Physiology

Year:

2012

Language:

english

File:

PDF, 1.43 MB

english, 2012

35

Visualization, Modeling, and Spatial Statistics of Mitochondrial Assembly in Adult Cardiomyocytes using Serial Block-Face Scanning Electron Microscopy

Yan, Jenny, Walker, Cameron G., O'sullivan, Michael J., Bushong, Eric A., Ellisman, Mark H., Hoshijima, Masahiko, Rajagopal, Vijayaraghavan

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 35 KB

english, 2012

36

Role of Vinculin in Ventricular Wall Function

Janssen, Matthew S., Tangney, Jared R., Liao, Peter, Zemljic-Harpf, Alice, Chuang, Joyce, Hoshijima, Masahiko, McCulloch, Andrew D., Ross, Robert S., Omens, Jeffrey H.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 39 KB

english, 2012

37

Mechanisms of dilated cardiomyopathies

Ralph H. Knöll, Masahiko Hoshijima, Kenneth R. Chien

Journal:

Drug Discovery Today: Disease Mechanisms

Year:

2004

Language:

english

File:

PDF, 237 KB

english, 2004

38

Reversal of Calcium Cycling Defects in Advanced Heart Failure: Toward Molecular Therapy

Masahiko Hoshijima, Ralph Knöll, Mohammad Pashmforoush, Kenneth R. Chien

Journal:

Journal of the American College of Cardiology

Year:

2006

Language:

english

File:

PDF, 2.21 MB

english, 2006

39

Percutaneous Cardiac Recirculation-Mediated Gene Transfer of an Inhibitory Phospholamban Peptide Reverses Advanced Heart Failure in Large Animals

David M. Kaye, Arthur Preovolos, Tanneale Marshall, Melissa Byrne, Masahiko Hoshijima, Roger Hajjar, Justin A. Mariani, Salvatore Pepe, Kenneth R. Chien, John M. Power

Journal:

Journal of the American College of Cardiology

Year:

2007

Language:

english

File:

PDF, 1.31 MB

english, 2007

40

Cardiac-Specific Deletion of SOCS-3 Prevents Development of Left Ventricular Remodeling After Acute Myocardial Infarction

Toyoharu Oba, Hideo Yasukawa, Masahiko Hoshijima, Ken-ichiro Sasaki, Nobuyoshi Futamata, Daisuke Fukui, Kazutoshi Mawatari, Takanobu Nagata, Sachiko Kyogoku, Hideki Ohshima, Tomoko Minami, Keiichiro N

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 5.45 MB

english, 2012

41

Effects of gene transfer of urokinase-type plasminogen activator on extracellular matrix and ventricular remodeling in swine

Hiroshi Ashikaga, Michael Barr, Leslie J. Hsu, Thomas Dieterle, Masahiko Hoshijima, John Ross Jr., Kenneth R. Chien, James W. Covell, Francisco J. Villarreal

Journal:

Journal of the American College of Cardiology

Year:

2003

Language:

english

File:

PDF, 312 KB

english, 2003

42

Genetic complementation identifies phospholamban- sarcoplasmic reticulum Ca ATPase interaction as the primary defect that drives the onset of heart failure in dilated cardiomyopathy

Susumu Minamisawa, Masahiko Hoshijima, Guoxiang Chu, Christopher A. Ward, Konrad Frank, Yusu Gu, John Ross Jr., Wayne R. Giles, Evangelia G. Kranias, Kenneth R. Chien

Journal:

Journal of Cardiac Failure

Year:

1999

Language:

english

File:

PDF, 155 KB

english, 1999

43

Novel Role for Vinculin in Ventricular Myocyte Mechanics and Dysfunction

Tangney, Jared R., Chuang, Joyce S., Janssen, Matthew S., Krishnamurthy, Adarsh, Liao, Peter, Hoshijima, Masahiko, Wu, Xin, Meininger, Gerald A., Muthuchamy, Mariappan, Zemljic-Harpf, Alice, Ross, Rob

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 915 KB

english, 2013

44

Purification and characterization from bovine brain membranes of a GTP-binding protein with a Mr of 21,000, ADP-ribosylated by an ADP-ribosyltransferase contaminated in botulinum toxin type C1 4- Identification as the rhoA gene product

Hoshijima, Masahiko, Kondo, Jun, Kikuchi, Akira, Yamamoto, Katsuhiko, Takai, Yoshimi

Journal:

Molecular Brain Research

Year:

1990

Language:

english

File:

PDF, 751 KB

english, 1990

45

Effects of Membrane Calcium Flux Localizations and Realistic T-Tubule Geometry on Cardiac Excitation-Contraction Coupling

Cheng, Yuhui, Yu, Zeyun, Hoshijima, Masahiko, Holst, Michael, McCulloch, Andrew, McCammon, Andrew, Michailova, Anushka

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 45 KB

english, 2010

46

New software developments for quality mesh generation and optimization from biomedical imaging data

Yu, Zeyun, Wang, Jun, Gao, Zhanheng, Xu, Ming, Hoshijima, Masahiko

Journal:

Computer Methods and Programs in Biomedicine

Year:

2014

Language:

english

File:

PDF, 8.13 MB

english, 2014

47

Modeling Calcium Sparks in a Three-Dimensional Reconstruction of a Cardiac Calcium Release Unit

Hake, Johan E., Edwards, Andrew G., Yu, Zeyun, Kekenes-Huskey, Peter, Michailova, Anushka P., McCammon, Andrew J., Holst, Michael J., Hoshijima, Masahiko, McCulloch, Andrew D.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 38 KB

english, 2012

48

3D Imaging of Nanoscopic Membrane Systems Regulating Cardiac Excitation-Contraction Coupling: Multi-Color Optical Super-Resolution and Serial Block-Face Scanning Electron Microscopy

Wong, Joseph Isaac S., Baddeley, David, Bushong, Eric A., Ellisman, Mark, Hoshijima, Masahiko, Soeller, Christian

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 41 KB

english, 2012

49

Nanoscale Distribution of Ryanodine Receptors and Caveolin-3 in Mouse Ventricular Myocytes: Dilation of T-Tubules near Junctions

Wong, Joseph, Baddeley, David, Bushong, Eric A., Yu, Zeyun, Ellisman, Mark H., Hoshijima, Masahiko, Soeller, Christian

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 946 KB

english, 2013

50

Reversing Advanced Heart Failure by Targeting Ca 2+ Cycling

Kaye, David M., Hoshijima, Masahiko, Chien, Kenneth R.

Journal:

Annual Review of Medicine

Year:

2008

Language:

english

File:

PDF, 1.13 MB

english, 2008

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